Posted: January 26th, 2018

A 35 years old client with ovarian cancer is prescribed hydroxyurea (Hydrea), an antimetabolite drug

A 35 years old client with ovarian cancer is prescribed hydroxyurea (Hydrea), an antimetabolite drug.

Antimetabolites are a diverse group of antineoplastic agents that interfere with various metabolic actions of the cell. The mechanism of action of antimetabolites interferes with:

A. cell division or mitosis during the M phase of the cell cycle.
B. normal cellular processes during the S phase of the cell cycle.
C. the chemical structure of deoxyribonucleic acid (DNA) and chemical binding between DNA molecules (cell cycle–nonspecific).
D. one or more stages of ribonucleic acid (RNA) synthesis, DNA synthesis, or both (cell cycle–nonspecific).