What drug causes an interaction with sulfonylureas, resulting in antagonistic action in which a larger dose may be required?

Endocrine, Reproductive, and Cardiovascular Drugs

Complete the following and submit your answers.

  • Chapter 23, page 470, Case Study B- Antidiabetic Agents and page 471, questions 1 through 10.
  • Chapter 25, page 494, questions 1 through 10.

Chapter 23, page 470, Case Study B – Antidiabetic Drugs

  1. The physician starts him on glyburide, a sulfonylurea medication.  He explains to Marcus that sulfonylureas work by:
  2. The physician explains to Marcus that one of the side effects of a sulfonylurea medication is:
  3. Prior to prescribing the medication, the physician reviews Marcus’s medical history.  This is because sulfonylureas must be used with extreme caution in individual’s who:
  4. The physician cautions Marcus to call him prior to taking any other medication because of possible interactions.  Which drug can potentiate the hypoglycemic effect of a sulfonylurea?
  5. What drug causes an interaction with sulfonylureas, resulting in antagonistic action in which a larger dose may be required?

Antidiabetic Agents and page 471, questions 1 through 10.

  1. Glucophage – Oral antidiabetic agent
  2. prednisone – Corticosteroid
  3. Humulin R – Insulin: short acting
  4. Synthroid – Thyroid agent
  5. Avandia – Oral antidiabetic agent
  6. Tapazole – Antithyroid
  7. Isophane – Insulin: intermediate acting
  8. Prandin – Oral antidiabetic agent
  9. Lantus – Insulin: long acting
  10. Humalog – Insulin: rapid acting

Chapter 25, page 494 (actually pg. 541), questions 1 through 10

  1. isosorbide – Angina
  2. Zetia – Elevated cholesterol
  3. Lovenox – Pulmonary emboli
  4. Cardizem – Hypertension
  5. Zocor – Elevated cholesterol
  6. Plavix – Stroke prevention (platelet inhibitor)
  7. Crestor – Elevated cholesterol
  8. hydralazine – Hypertension
  9. quinidine – Cardiac arrhythmia
  10. procainamide – Cardiac arrhythmia

 

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