Posted: April 12th, 2017

What drug causes an interaction with sulfonylureas, resulting in antagonistic action in which a larger dose may be required?

Endocrine, Reproductive, and Cardiovascular Drugs

Complete the following and submit your answers.

• Chapter 23, page 470, Case Study B- Antidiabetic Agents and page 471, questions 1 through 10.
• Chapter 25, page 494, questions 1 through 10.

Chapter 23, page 470, Case Study B – Antidiabetic Drugs

1. The physician starts him on glyburide, a sulfonylurea medication.  He explains to Marcus that sulfonylureas work by:
2. The physician explains to Marcus that one of the side effects of a sulfonylurea medication is:
3. Prior to prescribing the medication, the physician reviews Marcus’s medical history.  This is because sulfonylureas must be used with extreme caution in individual’s who:
4. The physician cautions Marcus to call him prior to taking any other medication because of possible interactions.  Which drug can potentiate the hypoglycemic effect of a sulfonylurea?
5. What drug causes an interaction with sulfonylureas, resulting in antagonistic action in which a larger dose may be required?

Antidiabetic Agents and page 471, questions 1 through 10.

1. Glucophage – Oral antidiabetic agent
2. prednisone – Corticosteroid
3. Humulin R – Insulin: short acting
4. Synthroid – Thyroid agent
5. Avandia – Oral antidiabetic agent
6. Tapazole – Antithyroid
7. Isophane – Insulin: intermediate acting
8. Prandin – Oral antidiabetic agent
9. Lantus – Insulin: long acting
10. Humalog – Insulin: rapid acting

Chapter 25, page 494 (actually pg. 541), questions 1 through 10

1. isosorbide – Angina
2. Zetia – Elevated cholesterol
3. Lovenox – Pulmonary emboli
4. Cardizem – Hypertension
5. Zocor – Elevated cholesterol
6. Plavix – Stroke prevention (platelet inhibitor)
7. Crestor – Elevated cholesterol
8. hydralazine – Hypertension
9. quinidine – Cardiac arrhythmia
10. procainamide – Cardiac arrhythmia